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What is SOOTHE?

The SOOTHE (Neuroactive Steroid to Treat Depressed MOOd: A Trial for PeoplE with HIV) Trial aims to determine the effects of pregnenolone and brain function, inflammation and depressive symptoms in people with HIV and depression. This randomized clinical trial is funded by the National Institutes of Health (NIH).

ClinicalTrial.gov Identifier: NCT05570812

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© 2023 | SOOTHE Trial - The Mukerji Lab for Neuroinfectious Diseases, MGB Neurology

Funded by the National Institute of Health (NIH)

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